Abstract
Cytogenetic investigation was attempted on 44 tumors from 44 patients with transitional
cell carcinoma (TCC) of the upper urinary tract (pelvis and ureter), and karyotypes
were obtained in 27 tumors. Numerical changes prevailed, but are not specific for
this type of tumor (trisomy 7, −Y, or both). In the light of previously reported data on TCC, the finding of a del(9q)
as the only anomaly in one of the cases may be meaningful. Patients showing −Y and/or trisomy 7 had a poor prognosis.
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Article info
Publication history
Accepted:
March 10,
1999
Received:
November 5,
1998
Identification
Copyright
© 1999 Elsevier Science Inc. Published by Elsevier Inc. All rights reserved.