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Corresponding author. Seok Joong Yun, M.D., Ph.D., Department of Urology, College of Medicine, Chungbuk National University, Chungdae-ro 1, Seowon-Gu, Ceongju, Chungbuk 28644, South Korea; Tel: +82-043-269-6371; Fax: +82-43-269-6144.
Fresh frozen tissues are the first choice for molecular analysis because genetic material in tissue samples stored at – 80 °C can be preserved for years . However, genetic material in fresh frozen tissue gradually degrades after 5 years of storage. To preserve genetic information for longer periods, tissues are often stored as formalin-fixed paraffin-embedded (FFPE) samples . FFPE tissue samples are essential for molecular diagnosis and retrospective clinical studies. FFPE tissue is more conveniently stored than fresh frozen tissue; it can be stored for decades, even at room temperature.